Tag Archives: lipids

LDL Cholesterol in China

Low-Density Lipoprotein Cholesterol, Cardiovascular Disease Risk, and Mortality in China is a study published in the JAMA Open Network. It is remarkable for the number of subjects studied – 3, 789, 025 participants!  They were categorized into low-risk, primary prevention, and secondary prevention cohorts based on their medical history and ASCVD (atherosclerotic cardiovascular disease) risk. The primary…


Read the full entry

Treatment of High Blood Cholesterol

Measurement of blood cholesterol concentration is another screening test that has been widely employed without good evidence for its utility. There is no doubt that patients with coronary artery disease (CAD) benefit from the lowering of their blood cholesterol with statin (Lipitor and similar drugs) therapy – so called secondary prevention. But most primary care…


Read the full entry

Trans Fats, Big Brother, and Sloppy Science

Be afraid. There’s a plot to poison you with fat, trans fats to be precise or trans fatty acids to be even more exact. There are two articles in the Annals of Internal Medicine (here and here) which give a pretty good idea where medicine is heading. You’ve likely heard about trans fats. Their chemical…


Read the full entry