I’ve written several articles about the difficulties inherent in screening for diseases that are common and associated with significant morbidity and mortality. The two most prominent are breast cancer and prostate cancer. Both have screening tests that are widely used, but the public and many physicians seem to be unaware of their limitations. Overdiagnosis is…
Former President Joe Biden’s diagnosis of metastatic prostate cancer may cause a lot of frightened seniors (>70) to react inappropriately. Some may ask their doctors for a PSA (prostate specific antigen) test despite the US Preventive Services Task Force’s recommendation not to screen for prostate cancer in men older than 70. The problem with PSA…
The press is quoting a bevy of “cancer experts” pontificating on how it’s inconceivable that the former president Biden didn’t have a PSA test while he was president. They seem to think that the PSA test is an infallible guide to the diagnosis and subsequent successful treatment of prostate cancer. The use of routine PSA…
Projected Lifetime Cancer Risks From Current Computed Tomography Imaging is a study just published in JAMA Internal Medicine. The study concludes: “That at current utilization and radiation dose levels, CT examinations in 2023 were projected to result in approximately 103,000 future cancers over the course of the lifetime of exposed patients. If current practices persist,…
The American Cancer Society has released its annual report on the incidence and mortality of cancer in the USA. The full report can be downloaded below. I’ll summarize the salient features of the ACS’s data. They come from registries that assembled the information (occurrence, outcomes, and incidence data) through the end of 2021 and mortality…
Screening for disease is not as straightforward as it may seem on cursory examination. Sometimes it does not influence the course of the screened for disease and other times it may cause more harm than good as early intervention may result in more morbidity than if the disease had been undiagnosed. Then there is the…
The US Preventive Services Task Force has issued a new draft recommending biennial screening mammography for women ages 40 to 74 years. This recommendation has received widespread notice in the lay press. Workers in the field along with breast cancer advocates want even more (annual) screening. Everybody commenting on this recommendation seems to support it…
The two subjects of the above title seem to have little in common. But they are both examples of action unmoored from knowledge. If the scientific foundation of medicine is compared to that of economics, specifically the actions of the world’s central banks, the practitioners of the former are certainly closer to the dictates of…
Every January the American Cancer Society publishes Cancer Statistics based on the most recent data available. The abstract from the report is immediately below. The entire report is available at the end of this article. Abstract: Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States…
For more than 25 years I have used the Head Start program to teach medical students data analysis, how to evaluate the therapeutic efficacy of treatment regimens, and how belief commonly trumps evidence. This process usually followed the recommendation of a course of treatment by a consultant to a patient who was on a general medicine service…