Category Archives: Featured

Gene Therapy for Sickle Cell Disease

Sickle Cell Disease is a disorder of hemoglobin production secondary to an alteration in the hemoglobin gene on chromosome 11.  Specifically, there is a single amino acid substitution in “adult” β A -globin (Glu6Val) stemming from a single base substitution (A→T) in the first exon of the human β A -globin gene. The abnormal nucleotide…


Read the full entry

Ostracism and “high Crimes and Misdemeanors”

Ostracism was an interesting feature of the Athenian democracy, if you can call a city-state which granted the suffrage only to adult male land owners a democracy. About 30 to 50 thousand of about 300 thousand Athenians were eligible to vote. Unsurprisingly, democracy in Athens lasted little more than a century. Ostracism derives its name from ostraka,…


Read the full entry

Salt Intake in Chronic Kidney Diease

How much salt people should eat continues to be a murky issue. A paper in the February 2017 issue of the American Journal of Kidney Diseases examines the issue of salt (actually sodium) intake on the prevention of cardiovascular disease in patients with chronic kidney diseases (CKD) stages 2-4. It is a commentary on an…


Read the full entry

The Vulture Has Landed

I’ve been out of the country for a few weeks, but am now back (see below for the gruesome details). Thus regular posting will resume. First the important stuff.  If you take a cruise bring your own salt and a shaker. No cruise line I know of has decent salt shakers. They tend to use…


Read the full entry

Life Expectancy in the Elderly

Americans have a lower life expectancy than people in other developed countries. This lower longevity has been often used to disparage medical care in this country as being inferior to that of other similarly advanced nations.  Such an accusation is made acute by the high cost of American medical care – the highest in the world….


Read the full entry

Statins For the Primary Prevention of Cardiovascular Disease

The use of statins (drugs which lower blood cholesterol) for the primary prevention of CV disease has been controversial since the drugs became available almost 30 years ago. Primary prevention is the prevention of a disease which the patient does not have, eg a stroke or a heart attack. Secondary prevention is the prevention of…


Read the full entry

Daisy For President

Can a dog run for President of the United States? The answer is an unequivocal yes! Let me quote the Constitution: No person except a natural born citizen , or a citizen of the United States, at the time of the Adaption of this Constitution shall be eligible to the Office of President; neither shall…


Read the full entry

The Genetically Modified Organism in Your House

Vermont in a spasm of enlightenment has mandated that all genetically modified foods sold in the Green Mountain State be so labeled. According to numerous polls 90% of the population of the USA thinks this a good idea. This is the same concerned and informed group that by an 80% margin supports labeling food that…


Read the full entry

Cosmosapiens – Book Review

Cosmosapiens by John Hands Subtitled Human Evolution from the Origin of the Universe, John Hands’ book attempts to explain the origin of the universe and our place in it; and he does so in less than 600 pages (about a quarter of a million words) including many tables and figures. Amazingly, except for a stumble towards…


Read the full entry

Verdi Chords

One of the most distinctive characteristics of Giuseppe Verdi’s operas is his use of chords to resolve or punctuate the moments of greatest emotional and dramatic tension as his story reaches a crisis point. This simple device would seem within the grasp of almost any composer, but Verdi’s use of it is unique. Below are five…


Read the full entry

Categories