Tag Archives: acute renal failure

Prevention of Contrast Associated Acute Kidney Injury

Clinicians have been worrying about contrast induced nephropathy for decades. I’m referring to acute kidney injury caused by the infusion of iodinated agents used as part of imaging studies such CT scans. Over time it became standard practice to infuse fluid such as saline or sodium bicarbonate solution as a preventative agent. Patients thought to…


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Prevention of Contrast-Associated Acute Kidney Injury

The infusion of iodinated contrast materials as an aid to a variety of imaging studies is associated with the development of acute renal failure (now typically called acute kidney injury). This nephropathy almost always occurs in predisposed patients. Risk factors include pre-existing kidney disease, advanced age (>75), diabetic nephropathy, and congestive heart failure. The common…


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When to Start Dialysis in Patients with Acute Kidney Injury

When to start renal replacement therapy in patients with AKI has been a serious and incompletely answered question for as long as dialysis has been available to treat it. The seriousness of this disorder derives from its frequency, associated mortality, and cost. The JAMA contains a new study, Effect of Early vs Delayed Initiation of Renal…


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Acute Kidney Injury and Clinical Outcomes

A paper in the Mayo Clinic Proceedings, Acute Kidney Injury Predicts Outcomes of Non–Critically Ill Patients, examines the effect of Acute Kidney Injury (AKI) on the clinical out comes almost 6000 patients at a community teaching hospital affiliated with Yale. AKI was deined as an increase in serum creatinine of at least 0.3mg/dL over 48…


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