Tag Archives: congestive heart failure

Transthyretin Cardiac Amyloidosis.

Transthyretin amyloidosis, also called ATTR amyloidosis, is a progressive and fatal disease that affects multiple organs. It comes in two versions – genetic and wild (spontaneous and not hereditary). ATTR Amyloidosis is caused by the accumulation of a genetically variant form or even the normal form of the protein, transthyretin, into amyloid fibrils. Transthyretin is…

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The Pathophysiology of Edematous Diseases

Below is a PowerPoint presentation that I will give to the South Plains Kidney Foundation Medical Symposium this coming Friday, May 3. PowerPoint Edema

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Nephritic Edema

Yesterday I mentioned Ludwig Eichna. One of his great contributions to medical pathophysiology was the delineation between congestive heart failure and a congestive state. He built on the ideas of John Peters at Yale. Peters observed that while all measurable fluid compartments in patients with CHF were expanded their kidneys acted as if volume were…

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